Home : What Contrast Dyes Might Be Involved in Nephrogenic Systemic Fibrosis?

What Contrast Dyes Might Be Involved in Nephrogenic Systemic Fibrosis?

Which Gadolinium-Based Contrast Dyes Might Be Involved in Nephrogenic Systemic Fibrosis?

Although a definite cause and effect relationship has not been established between Gadolinium-based contrast dyes and Nephrogenic systemic fibrosis, there does seem to be a strong correlation between the two. In particular, four of these contrast dyes seem to have been implicated including Omniscan, MultiHance, Magnevist, and OptiMARK.

FDA-Approved Gadolinium Based Contrast Dyes and Nephrogenic Systemic Fibrosis

The FDA has approved five gadolinium-based contrast dyes for use in MRI scans including Magnevist, MultiHance, Omniscan, OptiMARK, and ProHance. These gadolinium-based contrast dyes are also often used in MRA, but they have not been approved for such scans. Out of these five contrast dyes, four of them have been implicated with Nephrogenic Systemic Fibrosis in kidney patients, and as such, the FDA has issued a warning regarding the use of these gadolinium-based contrast dyes.

Reports of Gadolinium-Based Contrast Dyes in Nephrogenic Systemic Fibrosis Cases

It is often difficult to determine exactly which gadolinium-based contrast dyes are involved in the case, since a number of patients receive multiple contrast dyes before being diagnosed with Nephrogenic Systemic Fibrosis. However, there are a few that do appear to occur more when specific agents are mentioned. Omniscan seems to be the one that is involved in most of the cases, with Magnevist and OptiMARK following.

How do the Gadolinium-Based Contrast Dyes Work?

All gadolinium-based contrast dyes work on the same principal in MRI scans and that is by means of its paramagnetic properties. The gadolinium contrast dye will be injected into the patient before the scan, and when this dye is put within a magnetic field, it will react differently causing a clearer image to show up on the scan.

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PERSONAL INFORMATION
First Name: *
Last Name: *
Address:
City:
State:
Zipcode:
Phone: -- ext.
Work Phone: -- ext.
E-mail Address: *

CASE INFORMATION
Have you been diagnosed with NSF (Nephrogenic Systemic Fibrosis) or NFD (Nephrogenic Fibrosing Dermopathy)? Yes No
When and where was the diagnosis made?
When did your problems start?

Describe your symptoms and how they developed.
Did you have an MRI (Magnetic Resonance Imaging) or MRA (Magnetic Resonance Angiography) scan done before your symptoms began? Yes No
Where and when was the scan (or scans, if more than one) done?
Did you have kidney failure, kidney function deficiency, or other kidney problems at the time the scan (or scans) were done? Yes No
Describe the kidney problems you had.
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